Zhang Jing-qin
2011
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Quality indicators
Journal
Journal of Chongqing Medical University
Abstract
Objective:To optimize the preparation of neostigmine bromide sustained-release tablets and to study its in-vitro drug release property.Methods:Hydrophilic matrix tablets and film coating were used to prepare neostigmine bromide sustained-release tablets and the in-vitro accumulated release rate of the formula was studied.Results:The releasing of the sustained-release tablets prepared here lasts 12 hours and fits the first-order releasing equation.Conclusion:The neostigmine bromide sustained release tablets obtain good releasing and are consistent with specification.