R. Zh
2013
Citations
0
Influential Citations
2
Citations
Journal
Fine Chemical Intermediates
Abstract
Ancitabine hydrochloride and its derivative cytarabine hydrochloride are important antileukemia drugs.Both compounds were synthesized starting from cytidine and reaction conditions were optimized.The overall yield of cytarabine hydrochloride was 32.2%,and the chemical structure was identified with IR,GC-MS and1H NMR spectra.The synthetic process is simple,convenient and easy to operate in industrial scale.