C. Liang, Shuanglin Qin, Xiaoji Wang
2016
Citations
0
Influential Citations
0
Citations
Journal
Journal name not available for this finding
Abstract
R)-tert-butyl 2,2-dimethyl-4-(prop-1-yn-1-yl)oxazolidine-3-carboxylate, an key intermediate of Biotin which is a water-soluble vitamin involved in an essential part of the metabolic cyle causing catalytic fixation of carbon dioxide in the biosynthesis of fatty acids, sugars, and α-amino acids, was synthesized from L-cystine in overall yield 41% through six steps, which included esterification, Boc protection, acetonization, reduction, Corey-Fuchs reaction.