F. Chimenti, A. Bolasco, S. Vomero
Jul 1, 1987
Citations
0
Influential Citations
1
Citations
Quality indicators
Journal
Il Farmaco; edizione scientifica
Abstract
The activity of copper and FAD dependent amine oxidases was tested with some derivatives of 3H-imidazo[4,5-h]quinoline and its isomers 3H-imidazo[4,5-f]quinoline, the chemistry of which is described in the literature (1), and Ki calculated. The methyl derivative of 3H-imidazo[4,5-f]quinoline was found to activate the copper bovine serum enzyme, but inhibits the FAD mitochondrial enzyme.