F. Havaldar, Abhay R. Patil
2008
Citations
0
Influential Citations
3
Citations
Journal
Heterocyclic Communications
Abstract
[4-(4-Oxo-2-phenyl-4H-quinazolin-3-yl)-phenoxy]-acetic acid [2-oxo-l,2dihydro-indol-3-ylidene]-hydrazide (7) on reaction with formaldehyde and various secondary amines in Ν,Ν-dimethyl formamide afforded Mannich bases [4-(4-oxo-2phenyl-4H-quinazolin-3-yl)-phenoxy]-acetic acid [1-substituted aminomethyl-2-oxo-l,2dihydro-indol-3-ylidene]-hydrazides (8a-d). The structures of the newly synthesized compounds have been confirmed by IR, *H NMR and mass spectra. The compounds have also been screened for their biological activity.