T. E. Goodwin, Xiang Zhou, P. Haile
2000
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0
Influential Citations
2
Citations
Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
A convenient synthesis of an isotopically-labelled version (13C,2H3) of the long-acting β2-adrenergic agonist, salmeterol, is described, starting from methyl salicylate, 1,6-dibromohexane and 4-phenyl-1-butanol. This compound was designed as an analytical internal standard for mass spectrometric determination of salmeterol in pharmacokinetic studies. Copyright © 2000 John Wiley & Sons, Ltd.