Christine Gauzy, Elisabeth Pereira, S. Faure
Sep 13, 2004
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
(+)-(1S,2R) and (−)-(1R,2S)-2-aminocyclobutane-1-carboxylic acids have been prepared in >97% ee and in 33% and 20% overall yields starting from a single, chiral, bicyclic compound perceived as a chiral uracil equivalent. Construction of the cyclobutane ring is achieved via a [2+2] photocycloaddition reaction of this chiral precursor with ethylene.