Xu Liang
2010
Citations
0
Influential Citations
0
Citations
Journal
Chemistry World
Abstract
2-Amino-6-bromopyridine and its derivatives are important pharmaceutical and chemical intermediates.2-Amino-6-bromopyridine was prepared with 2-amino6-methylpyridine as raw material by diazotization,bromation,oxidation,chlorination,amination and Hofmann degradation.The effects of the reaction conditions of chlorination,amination and Hofmann degradation on the yield were investigated.The total yield was 34.6%.The structure of product was identified by IR and ~1H NMR spectroscopy.