Tsuyuka Sugiishi, C. Matsumura, H. Amii
Mar 5, 2020
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0
Influential Citations
2
Citations
Journal
Organic & biomolecular chemistry
Abstract
The synthesis of 3-fluoro-2,5-disubstituted furans from gem-difluorocyclopropyl ketones was accomplished using trifluoromethanesulfonic acid (CF3SO3H) through ring expansion owing to the activation of the carbonyl group in the starting material. The present synthesis of 3-fluorofurans tolerates substrates designed for products with aromatic substituents at the C-2 and C-5 positions.