W. Hua
2004
Citations
0
Influential Citations
1
Citations
Journal
Chinese New Drugs Journal
Abstract
Objective:To synthesize 3-pyridineacetic acid hydrochloride. Methods:Starting from 3-acetylpyridine prepared by esterfication and condensation of nicotic acid, 3-pyridineacetic acid hydrochloride was synthesized from the intermediate 3-pyridylthioacetmorpholide via hydrolysis and acidification. Results and Conclusion:The process is more moderate and simpler with overall yield of 51.0%.