Chemoenzymatic synthesis of (3R,4S)- and (3S,4R)-3-methoxy-4-methylaminopyrrolidine

doi:10.1016/J.TETASY.2006.10.031

Paper

DOI: 10.1016/J.TETASY.2006.10.031

Chemoenzymatic synthesis of (3R,4S)- and (3S,4R)-3-methoxy-4-methylaminopyrrolidine

Published Nov 6, 2006 · A. Kamal, Ahmad Ali Shaik, Mahendra Sandbhor

Tetrahedron-asymmetry

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Abstract

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Study Snapshot

This study presents an efficient and convenient enantioselective synthesis of (3R,4S)-3-methoxy-4-methylaminopyrrolidine using a lipase-mediated resolution protocol.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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