F. Gaudemar-Bardone, M. Mladenova
Jun 1, 1990
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Journal
Synthetic Communications
Abstract
Abstract Several 3-substituted ethyl 4,4,4-trichloro-2-cyanobutanoates (2, 3 and 4) are synthesized in good to excellent yields and high stereoselectivity by the one-pot reaction of ethyl 4,4,4-trichloro-2-cyano-2-butenoate with various bifunctional nucleophilic reagents.