G. Hartman, W. Halczenko
Oct 1, 1991
Citations
0
Influential Citations
9
Citations
Journal
Synthetic Communications
Abstract
Abstract N-Boc-4-Aminomethyl-L-phenylalanine is prepared from N-Boc-4-Iodophenylalanine in 78% yield over three steps. The method features an efficient Pd-catalyzed carbonylation, oxime formation, and subsequent catalytic reduction employing an ethanol/water/acetic acid solvent system which is crucial to successful reaction.