B. Pete, G. Parlagh, L. Tőke,
Dec 1, 2003
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0
Influential Citations
4
Citations
Journal
Heterocycles
Abstract
New synthetic intermediates, ethyl 5-formyl-1H-indole-2-carboxylates (4) were prepared from 2-ethoxycarbonyl-1H-indole-5-methanesulfonic acids (1). The transformation of the sulfomethyl group to formyl function was accomplished through elimination of SO 2 to yield ethyl 5-chloromethyl-1H-indole-2-carboxylates (2), hydrolysed to ethyl 5-hydroxymethyl-1H-indole-2-carboxylates (3), then oxidized to aldehydes (4).