F. Manfre, J. Pulicani
1994
Citations
0
Influential Citations
29
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract Pyrrolidine derivatives have been identified as a new class of non-peptide CCK antagonists. Enantiomers of RP 66803 , a representative compound of this chemical family were previously prepared by chiral chromatography of the racemate. In order to determine the absolute configuration of each one, we report herein an enantiospecific synthesis leading to the (+)-isomer using anodic methoxylation as key step.