E. Nurieva, N. Zefirov, N. S. Zefirov
Sep 1, 2015
Citations
0
Influential Citations
2
Citations
Journal
Russian Chemical Bulletin
Abstract
The work describes the synthesis of 2-adamantyl 7-[(2-{[(2E)-3-(3-hydroxy-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)prop-2-enoyl]amino}ethyl)amino]-7-oxoheptanoate and 7-[(2-{[(2E)-2-(3,4-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoyl]amino}ethyl)amino]-7-oxoheptanoate. The latter compound exhibits moderate cytotoxicity (EC50 = 4.8 μmol L–1) against the human epithelial lung carcinoma cells A549.