Synthesis and antibacterial activity of some new 1-heteroaryl-5-amino-4-phenyl-3-trifluoromethylpyrazoles.

doi:10.1016/J.EJMECH.2005.03.021

Paper

Synthesis and antibacterial activity of some new 1-heteroaryl-5-amino-4-phenyl-3-trifluoromethylpyrazoles.

Published 2005 · Vinod Kumar, Ranjana Aggarwal, Parikshit Tyagi

European journal of medicinal chemistry

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66

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Abstract

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Study Snapshot

Two new 1-heteroaryl-5-amino-4-phenyl-3-trifluoromethylpyrazoles show antibacterial activity comparable to commercial antibiotics.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis and antibacterial activity of some new 1-heteroaryl-5-amino-4-phenyl-3-trifluoromethylpyrazoles.

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References

New potent antihyperglycemic agents in db/db mice: synthesis and structure-activity relationship studies of (4-substituted benzyl) (trifluoromethyl)pyrazoles and -pyrazolones.

WAY-123783 shows potential as a new class of potent antihyperglycemic agents by selectively inhibiting renal tubular glucose reabsorption in obese, diabetic db/db mice.

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