Synthesis and biological activity of a novel series of 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides.

Paper

Synthesis and biological activity of a novel series of 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides.

Published Dec 1, 2003 · M. Himaja, Rajiv, M. Ramana

Bollettino chimico farmaceutico

UNKNOWN SJR score

5

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Abstract

A series of new 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides have been synthesized by coupling the 4-[2'-(6'-nitro)benzimidazolyl]benzoic acid with amino acid methyl esters/dipeptides using DCC as the coupling agent. All the synthesized compounds were found to exhibit potent anthelmintic activity along with moderate antimicrobial activity.

Study Snapshot

The synthesized 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides show potent anthelmintic activity and moderate antimicrobial activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis and biological activity of a novel series of 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides.

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References

Citations

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Peptide derivatives of iodoquinazolinones/nitroimidazoles show promising antimicrobial, antifungal, and anthelmintic activities against pathogenic microbes and earthworm species.

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