Yang Gui-chun
2009
Citations
0
Influential Citations
0
Citations
Journal
Journal of Hubei University
Abstract
(S)-4-benzylthiazolidine-2-thione,used as chiral auxiliary,was N-acylated by crotonyl chloride,and asymmetrically Michael reaction with 1-bromobutane,followed by cleavage using NaBH4 to give(R)-3-methylheptan-1-ol,which ordinally proceeded cyanidation,hydrolysis,etc to successfully synthesize the aggregation pheromone of rhinoceros beetles.The enantiomeric exess of the total synthesis is over 93% e.e.and the total yield was up to 39.45%.