B. Giese, T. Linker
1992
Citations
0
Influential Citations
13
Citations
Journal
Synthesis
Abstract
The ammonium salt of 3-deoxy-D-manno-2-octulosonic acid (10) is synthesized from D-lyxose (2) via 1,2,3,4-tetra-O-acetyl-5-bro mo-α-D-lyxopyranose (3) and radical C,C-bond formation with tert-butyl 2-(tributylstannylmethyl)propenoate (6). After deprotection and reduction, ozonolysis of 2,3-dideoxy-2-methylene-D-manno-octonic acid (9) yields the target molecule 10