V. L. Gein, O. V. Bobrovskaya, R. Valiev
Dec 1, 2015
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Journal
Pharmaceutical Chemistry Journal
Abstract
Reaction of the methyl esters of aroylpyruvic acids with mixtures of 4-(2-aminoethyl)benzenesulfonamide and an aromatic aldehyde was used to synthesize 1-[2-(4-aminosulfonylphenyl)ethyl]-5-aryl-4-aroyl-3-hydroxy- 3-pyrrolin-2-ones. The structures of these compounds were verified by IR and 1H NMR spectroscopy and mass spectrometry. Their antibacterial activity was studied.