SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SOME N-(3-HYDROXY-2-PYRIDYL) BENZAMIDES

doi:10.1515/HC.2006.12.6.427

Paper

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SOME N-(3-HYDROXY-2-PYRIDYL) BENZAMIDES

Published 2006 · A. Mobinikhaledi, N. Forughifar, S. Shariatzadeh

Heterocyclic Communications

Q3 SJR score

4

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

N-(3-Hydroxy-2-pyridyl)benzamides 3(a-J) were synthesized under weak basic solution by reacting of 2-amino-3-pyridinol and an appropriate carboxylic acid chloride, obtained by reaction of carboxylic acids with thionyl chloride. The microbiological activity of these compounds was tested in vitro against Escherichia Coil (PTCC 1338), Pseudomonas aeruginosa (PTCC 1074), Entrococcus faecalis (PTCC 1237) and Staphylococcus aureus (PTCC 1119) bacteria. Compounds 3a, 3e and 3f were the active benzamide derivatives against the Ef and Sa bacteria with a MIC value of 128 μ§/ηι1. Compound 3g was the active entry against Ec and Pa bacteria with a MIC value of 128 μg/. Keywords'. 3-Hydroxypyridyl, Benzamide, 2-Amino-3-pyridinol, Bacteria

Study Snapshot

N-(3-Hydroxy-2-pyridyl)benzamides show antibacterial activity against Escherichia Coil, Pseudomonas aeruginosa, Entrococcus faecalis, and Staphylococcus aureus

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SOME N-(3-HYDROXY-2-PYRIDYL) BENZAMIDES

Sign up to use Study Snapshot

References

Citations