H. Fahmy, A. El-masry, S. H. Ali Abdelwahed
Feb 1, 2001
Citations
0
Influential Citations
19
Citations
Journal
Archives of Pharmacal Research
Abstract
A series of 2-methylbenzimidazole incorporated to different heterocycles through ethyl or carbamoylethyl groups at position1 of benzimidazole were synthesized. Also 3-(2-methylbenzimidazol-1-yl)propanoic acid hydrazide incorporated with semicarbazides and thiosemicarbazides were prepared. Moreover, the triazole5e underwent Michael addition and alkylation reaction. Some of the newly synthesized compounds showed considerable antimicrobial activity against gram positive, negative bacteria and yeast.