Pandey K. Sarvesh, K. Nizamuddin
Jul 1, 2008
Citations
0
Influential Citations
26
Citations
Journal
Archiv der Pharmazie
Abstract
A series of 2‐(arylidene)‐indan‐1, 3‐diones 1 were prepared by Knoevenagel reaction between indane‐1,3‐dione and the appropriate araldehydes. The α,β‐enones 1 have been used as a component of Michael addition with equimolar amounts of 2‐aminopyridine/2‐aminopyrimidine to give novel heterocyclic systems 4 and 5, respectively. They are reported here for the first time. The structures of the newly synthesized compounds were confirmed by IR, 1H‐NMR, 13C‐NMR, and elemental analysis. All compounds were screened for their antibacterial and antifungal activities. Some of them showed promising activities.