A. Markosyan, N. M. Torshirzad, G. H. Shakhbazyan
Mar 1, 2014
Citations
0
Influential Citations
2
Citations
Journal
Pharmaceutical Chemistry Journal
Abstract
Ethyl 2-cyano-3,3-dimethyl-4-phenylbutanoate was cyclized into 1-amino-3,3-dimethyl-3,4-dihydronaphthalene-2-ethylcarboxylate, condensation of which with isothiocyanates synthesized 3-substituted 5,5-dimethyl-2-thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-ones. The antineoplastic properties of the synthesized compounds were studied.