A. A. Aghekyan, G. G. Mkryan, H. Panosyan
Mar 1, 2020
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0
Influential Citations
2
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Journal
Russian Journal of Organic Chemistry
Abstract
Gewald reaction of 4-oxo-1-phenylcyclohexane-1-carbonitrile with ethyl cyanoacetate and elemental sulfur in the presence of diethylamine afforded ethyl 2-amino-6-cyano-6-phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate which was treated with a series of acid chlorides to obtain the corresponding 2-amido derivatives. Condensation of the latter with hydrazine hydrate gave new fused benzothienopyrimidines. The synthesized compounds were screened for antioxidant activity.