N. Z. Hakobyan, Z. A. Hovasyan, S. S. Hovakimyan
Mar 1, 2020
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Journal
Russian Journal of General Chemistry
Abstract
Aminomethylation of 3-methyl-3-ethylpyrrolidin-2,5-dione (ethosuximide) and 3-(4-isopropoxyphenyl)pyrrolidine-2,5-dione (pufemide) with a 25% aqueous formalin solution and alkyl(aryl)amines yielded corresponding N-aminomethyl derivatives. The antioxidant activity of the synthesized compounds and their effect on some parameters of the blood coagulation system were studied.