V. Pothuri, P. Machiraju, V. Rao
May 1, 2020
Citations
0
Influential Citations
3
Citations
Journal
Russian Journal of General Chemistry
Abstract
Some novel isoxazole derivatives of 4-[5-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)isoxazole-3-yl]benzoic acid bearing biologically active pharmacophores like benzodioxane and peptide bond have been synthesized, and their structures are supported by FTIR,1H and 13C NMR, and mass spectra. The title compounds have been tested for antimicrobial and antioxidant activities. Molecular docking of the structures has also been carried out with protein Sortase A, according to which some compounds are characterized as potentially antimicrobial agents. Four products demonstrate strong antioxidant activity.