S. G. Jagadhani, S. G. Kundalikar, B. Karale
Dec 31, 2014
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Journal
Oriental journal of chemistry
Abstract
Bromo-2-fluorobenzaldehyde when treated with substituted hydroxyacetophenones yields chalcones 3. These chalcones were cyclized using DMSO/I2 gave the compound 2-(4- Bromo-2-fluorophenyl)-4H-chromen-4-one 4. Chalcones on treatment with DMSO/CuCl 2 yields 2- (4-bromo-2-fluorophenyl)-3-chloro-4H-chromen-4-one 5. The structures of compounds have been established on the basis of spectral data. These compounds were screened for their antimicrobial activities.