W. Bo
2007
Citations
0
Influential Citations
0
Citations
Journal
Fine chemicals
Abstract
3-Methyl-4-acetaminobenzenesulfonyl chloride(Ⅰ) was prepared from o-methylaniline by protecting the amino group and then reacting with chlorosulfonic acid.Then p-aminoacetanilide and Ⅰ in mole ratio 1∶1.1 reacted in w(CH3COOH)=5% acetic acid at 45 ℃ for 2 h,and their condensation product was hydrolyzed to give 3′-methyl-4,4′-diaminobenzenesulfonanilide in 89.37% yield.Similarly,with p-methoxylaniline,2-methoxy-5-acetaminobenzenesulfonyl chloride was prepared and converted to 2′-methoxy-4,5′-diaminobenzenesulfonanilide in 87.68% yield.Both products were charactered by IR,1HNMR,13CNMR and MS.