Muhammad Said, J. Ahmad, W. Rehman
Aug 1, 2015
Citations
0
Influential Citations
9
Citations
Journal
Inorganica Chimica Acta
Abstract
Abstract A series of novel trisubstituted guanidines of general formula C4H9CONHC(NHR1)NR2 (where R1 = 2-methoxyphenyl (1–4) and phenyl (5), R2 = 2-methoxyphenyl (1), phenyl (2), 2-tolyl (3), 2-chlorophenyl (4) and 2,3-dimethylphenyl (5), and their copper(II) complexes of general formula (C4H9CONHC(NR1)NR2)2Cu were synthesized in good yield. The synthesized guanidines and their copper(II) complexes were characterized by using elemental analysis, FT-IR, NMR (1H, 13C), and magnetic susceptibility measurements. Compounds 2, 3 and 5a were also characterized by single crystal X-ray diffraction analysis (XRD). Spectroscopic studies confirmed the bidentate coordination of ligands with copper center through oxygen and nitrogen atoms. All the synthesized compounds were tested against various bacterial strains, which showed that 1a and 4a exhibit good bactericidal activity.