T. Nagasaka, T. Imai
Jan 15, 1997
Citations
0
Influential Citations
15
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
The chiral pyrrolidine derivatives, 4-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-2-ones (10 and 11) and 5,5-disubstituted 2-pyrrolidinones (20, 21 and 22), were synthesized starting from (S)-pyroglutamic acid and absolute configuration determination was made based on the 1 H-NMR spectra of the bicyclic lactam intermediates.