Chen Nian-gen, Liu Xinyong, Ren Zhao-ping
2007
Citations
0
Influential Citations
1
Citations
Journal
Chinese Journal of Pharmaceuticals
Abstract
Clinofibrate, an antilipidemic agent was synthesized from cyclohexanone by electrophilic substitution with phenol to give 1,1-bis(4-hydroxyphenyl)cyclohexane, which was subjected to condensation with ethyl 2-bromo-2- methylbutanoate and then hydrolysis with an overall yield of 43%.