Ying-xin Li, Yichun Zhang, Tiantian Guo
2006
Citations
0
Influential Citations
13
Citations
Journal
Synthesis
Abstract
(25R)-5a-Spirostan-2a,3b-diol (gitogenin) 3β-O-[2-O-(α-L-rhamnopyranosyl)-β-D-galactopyranoside] (1), a cytotoxic spirostan saponin isolated from the underground parts of Hosta longipes (Liliaceae), was concisely synthesized. In this context, its congeners 2-4 were also prepared. All four compounds showed comparable potency to dioscin in inhibition against the growth of tumor cells.