Synthesis of ethyl 4-(isoxazol-4-yl)-2,4-dioxobutanoates from ethyl 5-aroyl-4-pyrone-2-carboxylates and hydroxylamine

doi:10.1016/J.MENCOM.2017.03.022

Paper

DOI: 10.1016/J.MENCOM.2017.03.022

Synthesis of ethyl 4-(isoxazol-4-yl)-2,4-dioxobutanoates from ethyl 5-aroyl-4-pyrone-2-carboxylates and hydroxylamine

Published Mar 1, 2017 · D. Obydennov, L. R. Khammatova, V. Sosnovskikh

Mendeleev Communications

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Abstract

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Study Snapshot

Ethyl 4-(5-arylisoxazol-4-yl)-2,4-dioxobutanoates can be synthesized from ethyl 5-aroyl-4-pyrone-2-carboxylates and hydroxylamine in ethanol at -20

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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