Chen Ying-qi
2007
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Journal
Chinese Journal of Synthetic Chemistry
Abstract
Ethyl 4-piperidingcarboxylate,which is an important intermediate,was synthesized from isonicotinic acid by esterification and hydrogenation.The yield of esterification,hydrogenation and the overall yield were 84.6%,87.0%,75.0%,respectively.The Pd/C can be reused 10 times.