Shen Zheng-rong
2007
Citations
0
Influential Citations
0
Citations
Journal
Chemical Reagents
Abstract
Ethyl 4-[(1-hydroxy-1-methyl)ethyl]-2-propyl-1H-imidazole-5-carboxylate,the key intermediate of Olmesartan,was synthesized from butanoic acid and o-phenylenediamine via condensation under microwave-irradiation,oxidation,esterification and the Gringard reaction.The overall yield of target product was 32.2%.