P. Wipf, Tingting Mo, Steven J. Geib
Sep 30, 2009
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Influential Citations
93
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Quality indicators
Journal
Organic & biomolecular chemistry
Abstract
Two novel SF5 analogs of the antimalarial agent mefloquine were synthesized in 5 steps and 10-23% overall yields and found to have improved activity and selectivity against malaria parasites. This work also represents the first report of SF5-substituted quinolines.