Synthesis and Evaluation of Insect Repellent Activity of 4-Amino-5-(4-bromobenzoyl)-3-ethyl-2(1H)-pyrimidone, on Setophilus oryzae (Coleo curculeonidae).

doi:10.1002/CHIN.200734148

Paper

Synthesis and Evaluation of Insect Repellent Activity of 4-Amino-5-(4-bromobenzoyl)-3-ethyl-2(1H)-pyrimidone, on Setophilus oryzae (Coleo curculeonidae).

Published Aug 21, 2007 · R. Toche, V. Medhane, A. Desai

ChemInform

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Abstract

One pot synthesis of 2-(4-bromobenzoyl)-3-ethylureidopropenenitrile (4) was obtained by heating 4-bromobenzoyl acetonitrile (1), ethylurea (2) and triethylorthoformate (3). Compound 4 was cyclized to target molecule 4-amino-5-(4-bromobenzoyl)-3-ethyl-2(lH)-pyrimidone (5) by sodiumethoxide. The insect repellent activity of 4 and 5 was evaluated on Setophilus oryzae (Coleo curculeonidae) at various concentrations.

Study Snapshot

4-Amino-5-(4-bromobenzoyl)-3-ethyl-2(1H)-pyrimidone effectively repels Setophilus oryzae at various concentrations, making it a promising insect repellent for crops.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Synthesis and Evaluation of Insect Repellent Activity of 4-Amino-5-(4-bromobenzoyl)-3-ethyl-2(1H)-pyrimidone, on Setophilus oryzae (Coleo curculeonidae).

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Applications of alkyl orthoesters as valuable substrates in organic transformations, focusing on reaction media

Alkyl orthoesters are efficient substrates for various organic reactions, offering eco-friendly, inexpensive, and safe solutions for organic transformations.