Anton V. Chernykh, I. O. Feskov, A. V. Chernykh
Feb 18, 2016
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron
Abstract
Abstract New non-flattened amino group-containing building blocks and fluorinated analogs based on the spiro[3.3]heptane motif were synthesized. The syntheses included a challenging deoxofluorination of sterically hindered carbonyl groups via an intermediate carbocation. The synthesized compounds could be useful in medicinal chemistry due to their three-dimensional shape, and a different pattern of the fluorine substitution.