Zilun Hu, W. Han
Jan 28, 2008
Citations
0
Influential Citations
10
Citations
Journal
Tetrahedron Letters
Abstract
Fluoro-containing amino acids, N-benzyloxycarbonyl-2-amino-4,4-difluorobutyric acid methyl ester and analogs, were prepared in high enantiomeric excess. Incorporation of 2-amino-4,4-difluoro butyric acid as P1 group provided a potent HCV NS3 protease inhibitor.