Qing Hou, Yifei Jing, X. Shao
Aug 1, 2017
Citations
0
Influential Citations
11
Citations
Journal
Chinese Chemical Letters
Abstract
Abstract 1,8-Naphthyridines (NAP) are biological important scaffolds in bioactive molecules design. By hybrid of NAP with neonicotinoid core structure, nine novel NAP derivatives were synthesized and subjected to insecticidal activities evaluation. Some of the compounds showed excellent insecticidal activity against cowpea aphids (Aphis craccivora) with LC50 values ranging from 0.011 mmol/L to 0.067 mmol/L. The results indicated that 1,8- naphthyridine can be used as insecticidal structure for further modification.