Wen-Zhen Zhang, T. Xia, Xu-Tong Yang
Mar 24, 2015
Citations
0
Influential Citations
30
Citations
Journal
Chemical communications
Abstract
The oxazolidine-2,4-dione motif is found frequently in biologically important compounds. A tandem phosphorus-mediated carboxylative condensation of primary amines and α-ketoesters/base-catalyzed cyclization reaction have been developed. These processes provide a novel and convenient access to various oxazolidine-2,4-diones in a one-pot fashion using atmospheric carbon dioxide and readily available substrates under very mild and transition-metal-free conditions.