B. B. Wylie, E. I. Isaacson, J. N. Delgado
Sep 1, 1965
Citations
0
Influential Citations
12
Citations
Journal
Journal of pharmaceutical sciences
Abstract
Esters and ethers of benzophenone oxime and dibenzosuberone oxime were synthesized as potential medicinal agents. The esterifications were effected by treating the oximes with benzoyl, 3,4,5-trimethoxybenzoyl, and diphenylcarbamyl chlorides. The O -alkylations of benzophenone oxime and dibenzosuberone oxime were accomplished by the nucleophilic substitution of γ -dimethylaminopropyl, β -dimethylaminoethyl, and benzyl chlorides. In the course of this investigation, 13 compounds were prepared for pharmacological evaluation.