Meng Zhao-li
2007
Citations
0
Influential Citations
4
Citations
Journal
Journal of Qingdao Agricultural University
Abstract
6,7-Dimethoxy coumarin was synthesized through 4 steps in this paper.Firstly,p-benzoquinone was prepared by oxidizing aniline with sodium bichromate and sulfuric acid.Secondly,hydroxyquinol triacetate was synthesized by reacting p-benzoquinone with acetic anhydride.Thirdly,6,7-dihydroxy coumarin was obtained by the cyclization of hydroxyquinol triacetate and malic acid.Lastly,6,7-dimethoxy coumarin was synthesized by methylating 6,7-dihydroxy coumarin with dimethyl sulfate.Both 6,7-dihydroxy coumarin and 6,7-dimethoxy coumarin had certain herbicidal activity against the root of Amaranthus retroflexus at 1 mg/ml,and the inhibitory rate against the root growth was close to or over 60.0%.6,7-dimethoxy coumarin had certain antifungal activity against four kinds of plant pathogens Valsa mali,Coniothyrium diplodiella,Physalospora piricolo,and Fusarium oxysporium;and the inhibitory rate against F.oxysporiumwas more than 85% at 0.5 mg/ml.