Zhu Yi-shen
2003
Citations
0
Influential Citations
1
Citations
Journal
Journal of Nanjing University
Abstract
The protected L-Lysine is an important material of solid phase peptide synthesis, which price is always high. This paper used Fmoc and Boc protection strategy, studied the synthesis procedure of protection for α-NH2 and e-NH2 of L-Lysine, chose the optimium synthesis condictions. The yield of Fmoc-L-Lys(Boc) was improved from 76% to 88% . The purity of product was 99.6% .