Richard N S van der Haas, J. A. Dekker, Jorma Hassfeld
Mar 2, 2017
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Influential Citations
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Citations
Journal
Synthesis
Abstract
Abstract An improved synthesis of the bicyclic spiro compound 2-oxa-6-azaspiro[3.3]heptane is presented. While this compound is often isolated as an oxalate salt, its isolation as a sulfonic acid salt yields a more stable and more soluble product. With these improved properties access to a wider range of reaction conditions with the spirobicyclic 2-oxa-6-azaspiro[3.3]heptane has been enabled.