S. Sayed, M. Raslan, K. Dawood
Mar 1, 2016
Citations
0
Influential Citations
5
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Reaction of 1-(5-acetyl-4-methylthiazol–2-yl)–3-phenylthiourea 2 with hydrazonoyl chlorides (3a, 3b, 3c, 3d, 3e, 3f) and 9 yielded the corresponding (thiazolyl)imino–1,3,4-thiadiazole derivatives (6a, 6b, 6c, 6d, 6e, 6f) and 12, respectively. Reaction of 2 with ethyl chloroacetate 13 gave (thiazolyl)imino-1,3-thiazolidin-4-one derivative 15, which upon condensation with aromatic aldehyde derivatives yielded the 5-benzylidene derivatives (16a, 16b). In addition, treatment of 2 with 3-chloropenta-2,4-dione 17 afforded the corresponding (thiazolyl)imino-1,3-thiazole derivative 19. The newly synthesized compounds were confirmed from their elemental analyses and spectral data.