Y. Terao, Yoichiro Ijima, H. Kakidani
Dec 15, 2003
Citations
0
Influential Citations
15
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
α-Methyl-α-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen) was prepared from the corresponding malonic acid derivative via asymmetric decarboxylation catalyzed by an enzyme, arylmalonate decarboxylase (EC 4.1.1.76), in high chemical and optical yields.