YamamotoYasuo, KatowHideki, SofukuShosuke
Jun 5, 1995
Citations
0
Influential Citations
3
Citations
Journal
Chemistry Letters
Abstract
RGDFPASS-containing cystine decapeptides were synthesized by the solution method. These peptides strongly inhibited platelet aggregation. N-Acetyl and C-methoxy peptide ([Phe5]-FR-1-AM) having amphiphilic structure exhibited especially high activity as a platelet aggregation inhibitor. A 240 kDa RGD-recognizing receptor was obtained from a sand dollar embryo by RGDFPASS-containing peptide-affinity chromatography.